Concepts and techniques in organic synthesis which are not covered in basic courses will be discussed with a focus on the enantioselective organocatalysis.
Advanced searches in online databases such as Reaxys and SciFinder Scholar.
The literature searches will focus on the design of a multistage synthesis of an organic compound that will be realized in the laboratory.
Professor's handouts and reviews and recent articles on the topics of the course.
Learning Objectives
Design, presentation, and achievement of a synthetic project through advanced organic synthesis techniques. Targeted researches of chemical literature.
The slides projected in class and some articles of literature useful to deepen the topics covered are available on the Moodle platform.
For organizational purposes, students interested in the practical experience must inform the teacher within the first two weeks of the start of the course.
Type of Assessment
Presentation and discussion of the assigned synthetic project. Written report on the synthesis carried out in laboratory including characterization of synthesized products and intermediates.
Oral examination concerning on general and mechanistic aspects of synthetic methods discussed during the course.
Course program
The course covers some advanced concepts and techniques of organic synthesis not addressed in basic courses with particular regard to the design and use of chiral organocatalysts.
The use of the databases Reaxys and Scifinder Scholar will be extensively analyzed.
The laboratory experience concerns the design, discussion, and achievement of a synthetic project with full characterization of intermediates and products.
Students will search suitable literature articles to support their own synthetic project.