Genome mapping, sequencing and assembly. Anatomy of eukaryotic, prokaryotic and viral genomes. Organization of the human genome. Cancer genomics and genomic texts in medicine. Use of molecular markers and genomic techniques for plant and animal genetic improvement and food safety.
- Genomes 4. Author: T.A. Brown. Editions: Edises. Chapters: 3, 4, 5, 7, 8, 9, 12
- Genetics and Genomics vol. III. Authors: Barcaccia and Falcinelli. Editions: Liguori. Chapters: 17, 20, 21
- Genetics and Genomics in the medical sciences. Strachan et al. Editions: Zanichelli. Chapters: 2.3, 2.4, 10, 11
- Genetics. Author: Binelli et al. Editions: editions. Chapter: 21.
Learning Objectives
The first part of this course aims to provide the student with knowledge relating to the structure and evolution of eukaryotic and prokaryotic genomes, as well as global analysis methodologies for mapping, sequencing and annotation of genomes. The topic of the transcriptome of the functional analysis of it will also be treated. The second part will deal with applied genomics topics concerning: 1) the structure, variability and organization of the human genome, 2) genetics and genomics of cancer, 3) genetic tests from genes to genomes, 4) genomic characterization, gene mapping and marker-assisted selection; 5) genomics and proteomics for genetic improvement and food safety.
Prerequisites
None
Teaching Methods
Frontal or online lessons.
Slides of the lessons on moodle
JOVE video link
Type of Assessment
Oral - in person or online - via Meet (Google).
Course program
Introduction to the course and to Genomics (1 hour).
Genome mapping (4 hours).
Genome sequencing (4 hours).
Genome annotation (4 hours).
Eukaryotic nuclear genomes (2 hours).
Genomes of prokaryotes and eukaryotic organelles (2 hours).
Viral genomes (2 hours).
Transcriptomics (3 hours)
Details, significance, organization and evolution of the human genome (3 hours).
Cancer Genetics and Genomics (4 hours).
Genetic tests from genes to genomes (4 hours).
Molecular markers and genomic analysis (2 hours).
Genomic characterization, gene mapping and marker-assisted selection (3 hours)
Genomics and proteomics to support genetic improvement and food safety (3 hours).
Student presentations on chosen topics (4 hours).
Laboratory practice (3 hours).