At the end of the course the students will:
be familiar with a significant number of bioinformatics and database tools; understand the underlying computational methods; be able to take full advantage of the capabilities of the tools; implement, execute and interpret the results of a pipeline of bioinformatic analyses.
FONDAMENTI DI BIOINFORMATICA M. Helmer Citterich; F. Ferrè, G. Pavesi, C. Romualdi, G. Pesole Ed. Zanichelli
Introduzione alla bioinformatica. G. Valle, M. Helmer Citterich, M. Attimonelli, G. Pesole. Ed. Zanichelli
Understanding bioinformatics. Marketa Zvelebil, Jeremy O. Baum Ed. CRC Press
Learning Objectives
The educational objectives include:
1) Basic knowledge of bioinformatics tools
2) Use of biological databases.
3) Alignment of protein sequences.
4) Structure-function relationship in proteins.
5) Interactions between biological molecules
The oral exam consists of a single interview. It focuses on questions related to the topics covered in the classroom and the tools applied in the lab.
To take the exam, students are required to register for the exam on the web site of the teaching enabled for electronic verbalization. The list is
closed two days before the date of the exam. Depending on the number of people who registered for the exam, it is possible that the exams will be scheduled over multiple dates, communicated at the beginning of the exam.
Course program
The course will consist of lectures and lab practicals on the following topics: servers and web servers; databases; access to data via queries; gene and protein sequence; alignments of sequences; profiles of sequences; clustering methods; structural alignments; structure-function relationship in proteins; protein interactions; biological networks: calculation, visualization and analysis; methods for structural modeling.