Rung & Dale Farmacologia – Rung H.P., Ritter J.M. and Flower R.J. -Elsevier Health
Farmacologia Generale e Molecolare- Clementi Francesco, Fumagalli Guido. Editore Edra
Goodman and Gilman- Le basi farmacologiche della terapia- Zanichelli.
Neuropsicofarmacologia:
Jerrold S. Meyer, Linda F. Quenzer Psicofarmacologia. Farmaci, cervello e comportamento, Edi. Ermes, 2010
Alan F. Schatzberg, Charles B. Nemeroff Psicofarmacologia vol. 1-3 (illustrato, brossura)
Centro Scientifico Editore – 2006
Carlson Neil R. Fisiologia del comportamento Piccin 2008
Julien RM, Advokat CD and Comaty JE. Droghe e farmaci psicoattivi. Edizioni Zanichelli
Learning Objectives
The pharmacological basis of the therapy of psychiatric pathologies and the effects of drugs of abuse. Representative drugs of the various therapeutic classes are treated: chemical nature, pharmacological actions, mechanism of action, therapeutic indications, pharmacokinetic characteristics, efficacy, safety, adverse effects, toxicity, contraindications, interactions with other drugs.
Prerequisites
None
Teaching Methods
Ex cathedra lessons
Further information
Reception hours: from Monday to Friday after appointment by e.mail.
Type of Assessment
Oral examination
Course program
Principles of Pharmacodynamics
Drug interactions with
- the receptors: characteristics of the drug/receptor link and transduction mechanisms
- desensitization and tachyphylaxis
- enzymes
- ion channels,
- the carrier molecules
Principles of neurotransmission
Anxiolytic drugs
Antipsychotic drugs
Antidepressant and antimanic drugs
Antiepileptic drugs
Amino acid system and memory
GABA and analeptic drugs
Opioid system and pain
Psychostimulants and hallucinogens (cocaine, amphetamines, LSD, cannabis)
Central roles adenosine and methylxanthines
Nicotine and smoking
Ethanol
Principles of drug addiction
Neurodegenerative diseases:
Parkinson's disease treatment
Huntington's disease treatment
Multiple sclerosis and amyotrophic lateral sclerosis and drugs
Rett syndrome
Alzheimer's dementia and treatments
Cerebral ischemia and drugs
Animal models for the study of drug effects :Intra and extracellular electrophysiological techniques for the study of drugs active in the central nervous system.