Molecular organization of cells and cellular homeostasis. DNA, chromosomes, RNA, protein synthesis. Regulation of gene expression. Elements of genetics. Bioenergetics: cellular respiration and fermentation. Molecular basis of action potential in excitable cells. Signal transduction: structure and function of receptors. Cycle of vision.
1) J R Morris, Daniel L Hartl, A H Knoll, R A Lue, Melissa Michael. Biologia Come funziona la vita- Cellula e Genetica. Edizione ZANICHELLI
2) A. Bevilacqua, P. Chieffi , et al. Basi molecolari e cellulari della vita. Edizione PICCIN 2020
3) Campbell "Biologia e Genetica" Edizione Pearson
4) David Sadava David M. Hillis H. Craig Heller Sally Hacker. Elementi di biologia e genetica. Edizione ZANICHELLI
Learning Objectives
The course, organized in theoretical lessons, aims to provide the basic information necessary for an understanding of the biological disciplines. The main topics of biology are covered such as the structure and organization of the cell, the basic mechanisms of cell metabolism and signal transduction.
In addition, the topics developed during the lectures should provide students with the knowledge to describe the basic biological structures and processes of the cell and living organisms using appropriate scientific terminology.
Prerequisites
none
Teaching Methods
Lectures (32 hrs)
Lesson slides provided by the teacher and uploaded on the e-learning platform of the university (access of students enrolled in the course through their own credentials).
https://e-l.unifi.it/course/view.php?id=35162
Further information
Student Reception: Friday 14.30 pm to 16 pm by mail appointment
Type of Assessment
Oral examination
Course program
Concept of life and living beings; cell theory, hints on the origin of life and evolution of cells.
The chemical basis of life. The elements, periodic table, carbon atom, functional groups. Chemical bonds. Importance of water pH, Osmosis.
Biological macromolecules: proteins and amino acids. Carbohydrates (disaccharides and polysaccharides), Lipids.
Prokaryotic and eukaryotic cells.
Biological membranes: structure and function. Fluid mosaic model.
Energy and metabolism. ATP Enzymes: function, biological importance, regulation. Metabolic pathways, Glycolysis; Fermentation; TCA; Oxidative phosphorylation.
Genome (DNA) and chromosomes. The cell cycle, mitosis and meiosis.
Watson and Crick DNA model. DNA replication, RNA transcription and protein synthesis. Hormones and Vitamins
The central dogma of biology. Genetic Code. Genes and gene regulation. Inheritance.
Genetically transmitted diseases: examples: Congenital retinopathy
Structure and function of receptors, generality of membrane receptors, particularities between ligand, second messenger, cAMP, Rhodopsin G protein coupled receptors (rhodopsin as protein, structure) signal transduction. Cycle of vision Vit. A, Lysozyme.